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Article

LINE-1 DNA methylation is inversely correlated with cord plasma homocysteine in man: A preliminary study

16 Aug 2009

Abstract excerpt

Folic acid supplementation during pregnancy has known beneficial effects. It reduces risk of neural tube defects and low birth weight. Folate and other one-carbon intermediates might secure these clinical effects via DNA methylation. However, most data on the effects of folate on the epigenome is derived from animal or in vitro models. We examined the relationship between cord blood methylation and maternal folic...

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Share to Congenital Anomalies and Fetal Surgery
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PMID: 19755846
DOI: 10.4161/epi.4.6.9766

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