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Folate and Epigenetics: Why we Should Not Forget Bacterial Biosynthesis

1 Sept 2018

Abstract excerpt

Folate, together with other B-vitamins, plays a crucial role in epigenetic regulation. Folate-mediated one-carbon metabolism refers to a complex network of interconnected metabolic pathways, which ultimately result in a supply of methyl groups for DNA, RNA or protein methylation. These epigenetic marks, particularly DNA methylation, have been proposed as plausible mechanisms underlying associations between folate...

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PMID: 30238776
DOI: 10.2217/epi-2018-0117

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