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Article

Genetic and non-genetic predictors of LINE-1 methylation in leukocyte DNA.

Environmental health perspectives - 1 Jun 2013

Tajuddin Salman M, Amaral André F S, Fernández Agustín F, Rodríguez-Rodero Sandra, Rodríguez Ramón María, Moore Lee E, Tardón Adonina, Carrato Alfredo, García-Closas Montserrat, Silverman Debra T, Jackson Brian P, García-Closas Reina, Cook Ashley L, Cantor Kenneth P, Chanock Stephen, Kogevinas Manolis, Rothman Nathaniel, Real Francisco X, Fraga Mario F, Malats Núria

Abstract excerpt

BACKGROUND: Altered DNA methylation has been associated with various diseases. OBJECTIVE: We evaluated the association between levels of methylation in leukocyte DNA at long interspersed nuclear element 1 (LINE-1) and genetic and non-genetic characteristics of 892 control participants from the Spanish Bladder Cancer/EPICURO study. METHODS: We determined LINE-1 methylation levels by pyrosequencing. Individual data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23552396
DOI: 10.1289/ehp.1206068
PMCID: PMC3672919

Genes

MTHFS
TCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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