Article
Proliferating cell nuclear antigen expression in childhood acute leukemia.
Blood - 1 Sept 1990
Keim D, Hailat N, Hodge D, Hanash S M
Abstract excerpt
Proliferating cell nuclear antigen (PCNA) is a 36-Kd nuclear protein, identified as the auxiliary protein of DNA polymerase delta, that is upregulated in activated proliferating cells from a variety of tissues and species, including human lymphocytes. We have examined by two-dimensional polyacrylamide gel electrophoresis the expression of PCNA in various subtypes of childhood acute leukemia and have found...
Topics
- Acute Disease
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antigens, CD
- Autoantigens
- Cell Cycle
- Child
- DNA, Neoplasm
- Electrophoresis, Gel, Two-Dimensional
- Female
- Humans
- Leukemia
