Article
Effects of two common polymorphisms in the 3' untranslated regions of estrogen receptor beta on mRNA stability and translatability.
BMC genetics - 15 Sept 2009
Putnik Milica, Zhao Chunyan, Gustafsson Jan-Ake, Dahlman-Wright Karin
Abstract excerpt
BACKGROUND: The present study represents the first attempt to functionally characterize two common single nucleotide polymorphisms (SNPs) in the 3'untranslated regions (3'UTRs) of estrogen receptor beta (ERbeta), focusing on the differences between alleles with regard to mRNA stability and translatability. These two ERbeta SNPs have been investigated for association with disease in a large number of reports....
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