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Article

A long AAAG repeat allele in the 5' UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells.

Breast cancer research and treatment - 1 Nov 2011

Galindo C L, McCormick J F, Bubb V J, Abid Alkadem D H, Li Long-Shan, McIver L J, George A C, Boothman D A, Quinn J P, Skinner M A, Garner H R

Abstract excerpt

We sequenced the 5' UTR of the estrogen-related receptor gamma gene (ERR-γ) in ~500 patient and volunteer samples and found that longer alleles of the (AAAG)(n) microsatellite were statistically and significantly more likely to exist in the germlines of breast cancer patients when compared to hea...

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Source

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Identifiers

PMID: 21153485
DOI: 10.1007/s10549-010-1237-9
PMCID: PMC3374865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21153485-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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