Article
Expression of alternatively spliced estrogen receptor alpha mRNAs is increased in breast cancer tissues.
The Journal of steroid biochemistry and molecular biology - 1 Nov 2001
Poola I, Speirs V
Abstract excerpt
We previously identified 20 different alternatively spliced estrogen receptor alpha (ERalpha) mRNAs that have deletions in various combinations of exons in breast cancer cell lines using a novel 'Splice Targeted Approach' [J. Steroid Biochem. Mol. Biol. 72 (2000) 249]. In the current study, we compared the frequency of alternatively spliced ERalpha variant expression in 35 reduction mammoplasty and 38 breast...
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