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Article

Influence of estrogen and variations at the BRCA1 promoter region on transcription and translation.

Molecular biology reports - 1 Jan 2014

Fernandes Lívia R, Costa Emmerson C B, Vargas Fernando R, Moreira Miguel A M

Abstract excerpt

We analyzed wild-type (WT) and four sequence variants of the BRCA1 promoter region-found in patients selected for hereditary breast and ovarian cancer syndrome-in respect to their influence on transcription and translation efficiencies in transient transfection assays in the presence or absence of estrogen. Five types of plasmids containing the EGFP reporter gene proceeded by WT 5'UTR-a, WT 5'UTR-b, and the three...

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Source

Identifiers

PMID: 24293149
DOI: 10.1007/s11033-013-2884-9

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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