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Article

Genetic variation in a4GnT in relation to Helicobacter pylori serology and gastric cancer risk.

Helicobacter - 1 Oct 2009

Zheng Zongli, Jia Yanbin, Hou Lifang, Persson Christina, Yeager Meredith, Lissowska Jolanta, Chanock Stephen J, Blaser Martin, Chow Wong-Ho, Ye Weimin

Abstract excerpt

BACKGROUND: Helicobacter pylori, a known risk factor of gastric cancer, rarely colonize the deeper portion of normal gastric glands, where the mucus is rich in alpha-1,4-linked N-acetylglucosamine capped O-glycans, that strongly inhibit H. pylori growth in vitro. MATERIALS AND METHODS: We investigated the association between genetic variation in the O-glycan transferase encoding gene (a4GnT) and H. pylori...

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Identifiers

PMID: 19751437
DOI: 10.1111/j.1523-5378.2009.00708.x
PMCID: PMC3008782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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