Article
Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.
European journal of cancer (Oxford, England : 1990) - 1 Jan 2012
Frank Bernd, Weck Melanie Nicole, Müller Heiko, Klopp Norman, Illig Thomas, Raum Elke, Brenner Hermann
Abstract excerpt
Mucins represent major components of the mucous layer in the stomach, protecting the underlying epithelium from acid, mechanical trauma, proteases and pathogenic bacteria. Previous studies have shown an association of neoplastic transformation in the stomach with aberrant mucin levels, suggesting a potential role of genetic variation in mucin genes in the development of gastric cancer (GC). We assessed the...
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