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Article

A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk.

BMC biology - 2 Aug 2018

Berthenet Elvire, Yahara Koji, Thorell Kaisa, Pascoe Ben, Meric Guillaume, Mikhail Jane M, Engstrand Lars, Enroth Helena, Burette Alain, Megraud Francis, Varon Christine, Atherton John C, Smith Sinead, Wilkinson Thomas S, Hitchings Matthew D, Falush Daniel, Sheppard Samuel K

Abstract excerpt

BACKGROUND: Helicobacter pylori are stomach-dwelling bacteria that are present in about 50% of the global population. Infection is asymptomatic in most cases, but it has been associated with gastritis, gastric ulcers and gastric cancer. Epidemiological evidence shows that progression to cancer depends upon the host and pathogen factors, but questions remain about why cancer phenotypes develop in a minority of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30071832
DOI: 10.1186/s12915-018-0550-3
PMCID: PMC6090961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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