Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Listeria monocytogenes ActA-mediated escape from autophagic recognition.

Nature cell biology - 1 Oct 2009

Yoshikawa Yuko, Ogawa Michinaga, Hain Torsten, Yoshida Mitsutaka, Fukumatsu Makoto, Kim Minsoo, Mimuro Hitomi, Nakagawa Ichiro, Yanagawa Toru, Ishii Tetsuro, Kakizuka Akira, Sztul Elizabeth, Chakraborty Trinad, Sasakawa Chihiro

Abstract excerpt

Autophagy degrades unnecessary organelles and misfolded protein aggregates, as well as cytoplasm-invading bacteria. Nevertheless, the bacteria Listeria monocytogenes efficiently escapes autophagy. We show here that recruitment of the Arp2/3 complex and Ena/VASP, via the bacterial ActA protein, to the bacterial surface disguises the bacteria from autophagic recognition, an activity that is independent of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin-Related Protein 2-3 Complex
Share to Autophagy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules

Share to Chimera

Share to Listeria monocytogenes

Share to Listeriosis

Share to Microfilament Proteins

Share to Ubiquitination

Source

Identifiers

PMID: 19749745
DOI: 10.1038/ncb1967

Genes

SQSTM1
VASP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Listeria monocytogenes ActA-mediated escape from autophagic recognition.PMID 19749745Read ↗

Listeria monocytogenesActA is a key player in evading autophagic recognitionSemantic proximity Read ↗

Bacterial Manipulation of Autophagy Across Mammalian Cells and Psyllid Vectors: Conserved Strategies, Divergent Mechanisms, and Evidence GapsSemantic proximity Read ↗

Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy.Semantic proximity Read ↗

Autophagy targeting of<i>Listeria monocytogenes</i>and the bacterial countermeasureSemantic proximity Read ↗

Stability of the Listeria monocytogenes ActA protein in mammalian cells is regulated by the N-end rule pathway.Semantic proximity Read ↗

Avoidance of Autophagy Mediated by PlcA or ActA Is Required for Listeria monocytogenes Growth in MacrophagesSemantic proximity Read ↗

Systematic mutational analysis of the amino-terminal domain of the Listeria monocytogenes ActA protein reveals novel functions in actin-based motility.Semantic proximity Read ↗

Secrets of a Successful Pathogen: Legionella Resistance to Progression Along the Autophagic PathwaySemantic proximity Read ↗

Listeria monocytogenes evades killing by autophagy during colonization of host cells.Semantic proximity Read ↗

p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways.Semantic proximity Read ↗

RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spreadSemantic proximity Read ↗

InlB: an invasion protein of Listeria monocytogenes with a novel type of surface association.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.