Article

Bacterial Manipulation of Autophagy Across Mammalian Cells and Psyllid Vectors: Conserved Strategies, Divergent Mechanisms, and Evidence Gaps

2026-07-07

Abstract excerpt

Autophagy restricts intracellular bacteria through xenophagy, yet many bacterial pathogens remodel this pathway to avoid degradation or support intracellular persistence. This review compares bacterial modulation of autophagy in mammalian cells and invertebrate vectors, with focusing on initiation, cargo recognition, autophagosome maturation, and autophagosome-lysosome fusion. In mammals, direct effector-host inte...

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Literature Corpus work: 8caca7bf-0035-5200-9585-cadf3213273d
DOI: 10.20944/preprints202607.0484.v1

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