Article
Multipyrene tandem probes for detection of C677T polymorphism in MTHFR gene.
Nucleic acids symposium series (2004) - 1 Jan 2009
Kholodar Svetlana A, Novopashina Daria S, Meschaninova Mariya I, Lomzov Alexander A, Venyaminova Alya G
Abstract excerpt
We designed tandems of oligo(2'-O-methylribonucleotides) conjugates containing two bispyrene (5'-bisPyr and 3'-bisPyr) groups on their junction for detection of C677T polymorphism in the methylenetetrahydrofolate reductase gene (MHTFR). The potential of SNP detection with multipyrene tandems of oligo(2'-O-methylribonucleotides) was demonstrated.
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