Article
Effect of polymorphisms in the β2-adrenergic receptor on the susceptibility and pulmonary function of patients with chronic obstructive pulmonary disease: a meta analysis.
Chinese medical journal - 1 Jun 2012
Niu Li-Ming, Liang Ying, Xu Ming, Zhang You-Yi, Zhang Yuan, He Bei
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous and complex disease of which the pathogenesis remains largely unknown. Many factors could influence COPD development and progression. One of them is the genetic risk factor. A severe hereditary deficiency of alpha-1 antitrypsin is the best genetic proof. Four single nucleotide polymorphisms (SNPs) of beta2-adrenergic receptor (β(2)AR)...
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