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Article

Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.

Pediatric research - 1 Sept 2009

Lee Beom Hee, Kwak Soo Heon, Shin Jae Il, Lee So Hee, Choi Hyun Jin, Kang Hee Gyung, Ha Il Soo, Lee Jae Seung, Dragon-Durey Marie-Agnès, Choi Yong, Cheong Hae Il

Abstract excerpt

Although genetic defect of complement factor H (CFH) is a common cause of atypical hemolytic uremic syndrome (aHUS), development of autoantibodies to CFH (CFH-Ab) is also known to be an acquired cause of aHUS. Recently, a correlation between the development of CFH-Ab and the deficiency of the CFH-related proteins, CFHR1 and CFHR3, was identified. In this study, plasma complement profiles were measured and genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19531976
DOI: 10.1203/PDR.0b013e3181b1bd4a

Genes

CFH
CFHR1
CFHR3
CFI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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