Article
Serotonin transporter deficiency in rats contributes to impaired object memory.
Genes, brain, and behavior - 1 Nov 2009
Olivier J D A, Jans L A W, Blokland A, Broers N J, Homberg J R, Ellenbroek B A, Cools A R
Abstract excerpt
Serotonin is well known for its role in affection, but less known for its role in cognition. The serotonin transporter (SERT) has an essential role in serotonergic neurotransmission as it determines the magnitude and duration of the serotonin signal in the synaptic cleft. There is evidence to suggest that homozygous SERT knockout rats (SERT(-/-)), as well as humans with the short SERT allele, show stronger...
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