Article
The impact of tryptophan depletion and 5-HTTLPR genotype on passive avoidance and response reversal instrumental learning tasks.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2007
Finger Elizabeth C, Marsh Abigail A, Buzas Beata, Kamel Niveen, Rhodes Rebecca, Vythilingham Meena, Pine Daniel S, Goldman David, Blair James R
Abstract excerpt
Transient reductions in serotonin levels during tryptophan depletion (TD) are thought to impair reward processing in healthy volunteers, while another facet of the serotonergic system, the serotonin transporter (5-HTTLPR) short allele polymorphism, is implicated in augmented processing of aversive stimuli. We examined the impact and interactions of TD and the serotonin promoter polymorphism genotype on reward and...
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