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Article

An Oxysterol-Binding Protein Family Identified in the Mouse

1 Aug 2002

Abstract excerpt

Oxysterols are oxygenated derivatives of cholesterol. They have been shown to influence a variety of biological functions including sterol metabolism, lipid trafficking, and apoptosis. Recently, 12 human OSBP-related genes have been identified. In this study, we have identified a family of 12 oxysterol-binding protein (OSBP)-related proteins (ORPs) in the mouse. A high level of amino acid identity (88-97%) was...

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PMID: 12215260
DOI: 10.1089/104454902320308942

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