Article
Survey of the association between polymorphisms of CTLA-4 exon 1 49 A/G genes with rheumatoid arthritis in Iran.
Journal of immunoassay & immunochemistry - 3 Sept 2022
Lashgari Mahin, Keshavarz Shahbaz Sanaz, Javadi Amir, Sahmani Mehdi, Khalaji Maryam, Maali Amirhosein, Foroughi Farshad
Abstract excerpt
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), which suppresses T cell proliferation, is a promising candidate for the susceptibility genes to rheumatic arthritis diseases (RA). This study aims to examine the association between the polymorphisms of the CTLA-4 exon 1(+ 49) genes with RA in the Qazvin city of Iran population. The polymerase chain reaction of genomic DNA-restriction fragment length...
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