Article
Polymorphisms in the nucleotide excision repair gene ERCC2/XPD and risk of non-Hodgkin lymphoma.
Cancer epidemiology - 1 Oct 2009
Worrillow Lisa, Roman Eve, Adamson Peter J, Kane Eleanor, Allan James M, Lightfoot Tracy J
Abstract excerpt
Non-Hodgkin lymphoma (NHL) represents a complex group of B- and T-cell malignancies characterised by chromosomal translocations. Since defects in DNA repair result in an increased frequency of chromosomal aberrations it has been hypothesised that genetic variation in DNA repair may be associated with risk of NHL. To investigate the relationship between DNA repair and NHL we analysed polymorphisms in XPD (R156R,...
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