Article
Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes.
Blood - 1 Nov 2006
Hill Deirdre A, Wang Sophia S, Cerhan James R, Davis Scott, Cozen Wendy, Severson Richard K, Hartge Patricia, Wacholder Sholom, Yeager Meredith, Chanock Stephen J, Rothman Nathaniel
Abstract excerpt
Chromosomal translocations, insertions, and deletions are common early events in non-Hodgkin lymphoma (NHL) carcinogenesis, and implicated in their formation are endogenous processes involved in antigen-receptor diversification, such as V(D)J recombination. DNA repair genes respond to the double- and single-strand breaks induced by these processes and may influence NHL etiology. We examined 34 genetic variants in...
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