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Article

Lack of evidence of a role of XBP1 and PRDM1 polymorphisms in Spanish patients with immunoglobulin A deficiency.

Human immunology - 1 Nov 2009

del Pozo Nadia, López-Mejías Raquel, Fernández-Arquero Miguel, Ferreira Antonio, García-Rodríguez Mari Cruz, de la Concha Emilio G, Fontán Gumersindo, Urcelay Elena, Núñez Concepción

Abstract excerpt

The etiology of selective immunoglobulin A deficiency (IgAD) is not yet unraveled, but genetics seem to play an important role. Defects in processes during B-cell differentiation into plasma cells could exist in these patients, turning the genes controlling these processes into interesting candidate genes for IgAD predisposition, as PRDM1 (encoding Blimp-1) and XBP1. We studied the involvement of several...

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Source

Identifiers

PMID: 19735688
DOI: 10.1016/j.humimm.2009.09.350

Genes

PRDM1
XBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Lack of evidence of a role of XBP1 and PRDM1 polymorphisms in Spanish patients with immunoglobulin A deficiency.PMID 19735688Read ↗

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