Article
Association of an NKG2D gene variant with systemic lupus erythematosus in two populations.
Human immunology - 1 Jan 2010
Kabalak Gamze, Thomas Rachel M, Martin Javier, Ortego-Centeno Noberto, Jimenez-Alonso Juan, de Ramón Enrique, Buyny Sabine, Hamsen Sandra, Gross Wolfgang L, Schnarr Sebastian, Zeidler Henning, Gromnica-Ihle Erika, Schmidt Reinhold E, Witte Torsten
Abstract excerpt
NKG2D, involved in T-cell activation and viral defense, shows a single-nucleotide polymorphism (SNP) in the transmembrane region, characterized by a substitution of alanine with threonine. We examined the association of systemic lupus erythematosus (SLE) with one of the NKG2D gene variants. We al...
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