Article
Allelic variants of CD40 and CD40L genes interact to promote antibiotic-induced cutaneous allergic reactions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 2009
Kim Sae-H, Lee J-E, Kim Sang-H, Jee Y-K, Kim Y-K, Park H-S, Min K-U, Park H-W
Abstract excerpt
BACKGROUND: The danger hypothesis provides a new perspective of the mechanisms underlying drug allergy. In this study, we evaluated associations between variations in the genes involved in danger signal pathways and antibiotic-induced cutaneous allergic reactions (AICARs). METHODS: Two hundred cases with urticaria, angio-oedema, maculopapular rash, and erythema multiforme caused by antibiotics were extracted from...
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