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Article

Genetic markers and danger signals in stevens-johnson syndrome and toxic epidermal necrolysis.

Allergology international : official journal of the Japanese Society of Allergology - 1 Dec 2010

Chung Wen-Hung, Hung Shuen-Iu

Abstract excerpt

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening adverse reactions, which could be induced by a variety of drugs. It was proposed that human leukocyte antigen (HLA)-restricted presentation of antigens (drugs or their metabolites) to T lymphocytes initiates the immune reactions of SJS/TEN. However, the genetic susceptibility and the exact pathogenesis were not clear until...

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Identifiers

PMID: 20962567
DOI: 10.2332/allergolint.10-RAI-0261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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