Article
Genetic susceptibility to respiratory syncytial virus infection in inbred mice.
Journal of medical virology - 1 May 2002
Stark James M, McDowell Susan A, Koenigsknecht Vincent, Prows Daniel R, Leikauf John E, Le Vine Ann Marie, Leikauf George D
Abstract excerpt
Differences in the severity of respiratory syncytial virus (RSV)-induced lower respiratory disease in infants have been attributed to multiple environmental and genetic factors. To identify the genetic factor(s) influencing RSV susceptibility, we examined RSV infection in eight inbred mouse strains. Lung RSV titers differed significantly between mouse strains: the RSV titers were 15-fold higher in AKR/J...
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