Article

Identification of deleterious and regulatory genomic variations in known asthma loci

2018-08-13

Abstract excerpt

<h4>Background</h4> Candidate gene and genome-wide association studies have identified hundreds of asthma risk loci. The majority of associated variants, however, are not known to have any biological function and are believed to represent markers rather than true causative mutations. We hypothesized that many of these associated markers are in linkage disequilibrium (LD) with the elusive causative variants. <h4>M...

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Literature Corpus work: 38da232d-4dca-567d-a60b-83ad9320447f
DOI: 10.1101/389031

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