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Article

Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease.

Neurogenetics - 1 May 2010

Soehn Anne S, Franck Thomas, Biskup Saskia, Giaime Emilie, Melle Christian, Rott Ruth, Cebo Daniel, Kalbacher Hubert, Ott Erwin, Pahnke Jens, Meitinger Thomas, Krüger Rejko, Gasser Thomas, Berg Daniela, von Eggeling Ferdinand, Engelender Simone, da Costa Cristine Alves, Riess Olaf

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic neurons and the presence of Lewy bodies. Alpha-synuclein and its interactor synphilin-1 are major components of these inclusions. Rare mutations in the alpha-synuclein and synphilin-1 genes have been implicated in the pathogenesis of PD; however, the normal function of these proteins is far from being...

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Identifiers

PMID: 19730898
DOI: 10.1007/s10048-009-0215-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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