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Article

Genetic association study of synphilin-1 in idiopathic Parkinson's disease.

BMC medical genetics - 21 Mar 2008

Myhre Ronny, Klungland Helge, Farrer Matthew J, Aasly Jan O

Abstract excerpt

BACKGROUND: Post-mortem Lewy body and Lewy neuritic inclusions are a defining feature of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). With the discovery of missense and multiplication mutations in the alpha-synuclein gene (SNCA) in familial parkinsonism, Lewy inclusions were found to stain intensely with antibodies raised against the protein. Yeast-two-hybrid studies identified synphilin-1 as an...

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Identifiers

PMID: 18366718
DOI: 10.1186/1471-2350-9-19
PMCID: PMC2329608

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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