Article
Inefficiency of C3H/HeN mice to control chlamydial lung infection correlates with downregulation of neutrophil activation during the late stage of infection.
Cellular & molecular immunology - 1 Aug 2009
Tang Xiaofei, Bu Xiaokun, Zhang Naihong, Li Xiaoxia, Huang Huanjun, Bai Hong, Yang Xi
Abstract excerpt
We previously reported that massive infiltration of neutrophils in C3H/HeN (C3H) mice could not efficiently control Chlamydia muridarum (Cm) infection and might contribute to the high susceptibility of these mice to lung infection. To further define the nature of neutrophil responses in C3H mice during chlamydial infection, we examine the expression of adhesion molecules and CD11b related to neutrophils...
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