Article
Using regulatory information to manipulate glycerol metabolism in Saccharomyces cerevisiae.
Applied microbiology and biotechnology - 1 Jan 2010
Hou Jin, Vemuri Goutham N
Abstract excerpt
Metabolic engineering has emerged as an attractive alternative to random mutagenesis and screening to design cell factories for industrial fermentation processes. The design of metabolic networks has been realized by gene deletions or strong overexpression of heterologous genes. There is an increasing body of evidence that indicates complete inactivation of native genes and high-level activity of heterologous...
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