Article
Genome-wide transcriptional response of a Saccharomyces cerevisiae strain with an altered redox metabolism.
Biotechnology and bioengineering - 5 Feb 2004
Bro Christoffer, Regenberg Birgitte, Nielsen Jens
Abstract excerpt
The genome-wide transcriptional response of a Saccharomyces cerevisiae strain deleted in GDH1 that encodes a NADP(+)-dependent glutamate dehydrogenase was compared to a wild-type strain under anaerobic steady-state conditions. The GDH1-deleted strain has a significantly reduced NADPH requirement, and therefore, an altered redox metabolism. Identification of genes with significantly changed expression using a...
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