Article
Combination of phosphorylated and truncated EGFR correlates with higher tumor and nodal stage in head and neck cancer.
Cancer investigation - 1 Dec 2010
Keller James, Shroyer Kenneth R, Batajoo Shishir K, Zhao Hong-Ling, Dong Li Ming, Hayman Michael J, Chan Edward L
Abstract excerpt
Epidermal growth factor receptor (EGFR) is a target in head and neck cancer. High EGFR expression and phosphorylated EGFR predicts poor survival in head and neck cancer patients, but does not correlate with advanced stage disease. The aim of this study is to determine if clinical biological correlates are more accurate when different aspects of EGFR are evaluated in combination. We analyzed the EGFR...
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