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Article

Rapid detection of rpoB gene mutations in rif-resistant M. tuberculosis isolates by oligonucleotide microarray.

Biomedical and environmental sciences : BES - 1 Jun 2009

Sun Ai-Hua, Fan Xing-Li, Li Li-Wei, Wang Li-Fang, Ans Wen-Ying, Yan Jie

Abstract excerpt

OBJECTIVE: To detect the specific mutations in rpoB gene of Mycobacterium tuberculosis by oligonucleotide microarray. METHODS: Four wild-type and 8 mutant probes were used to detect rifampin resistant strains. Target DNA of M. tuberculosis was amplified by PCR, hybridized and scanned. Direct sequencing was performed to verify the results of oligonucleotide microarray. RESULTS: Of the 102 rifampin-resistant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19725469
DOI: 10.1016/s0895-3988(09)60053-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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