Article
A novel genotypic test for rapid detection of multidrug-resistant Mycobacterium tuberculosis isolates by a multiplex probe array.
Journal of applied microbiology - 1 Oct 2007
Zhang S-L, Shen J-G, Xu P-H, Li D-X, Sun Z-Q, Li L, Yang Z-R, Sun Q
Abstract excerpt
AIMS: To develop and evaluate a novel genotypic test for rapid detection of rifampicin and isoniazid resistance of multidrug-resistant (MDR) Mycobacterium tuberculosis isolates by a multiplex probe array. METHODS AND RESULTS: A multiplex probe array was designed for genotypic test to simultaneously screen the mutations of rpoB, katG, inhA and ahpC genes, associated with rifampin and isoniazid resistance in M....
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