Article
Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone.
BMC cancer - 28 Aug 2012
van Oosterwijk Jolieke G, de Jong Danielle, van Ruler Maayke A J H, Hogendoorn Pancras C W, Dijkstra P D Sander, van Rijswijk Carla S P, Machado Isidro, Llombart-Bosch Antonio, Szuhai Karoly, Bovée Judith V M G
Abstract excerpt
BACKGROUND: Chondrosarcoma is the second most common primary sarcoma of bone. High-grade conventional chondrosarcoma and dedifferentiated chondrosarcoma have a poor outcome. In pre-clinical research aiming at the identification of novel treatment targets, the need for representative cell lines and model systems is high, but availability is scarce. METHODS: We developed and characterized three cell lines, derived...
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