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Article

C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division.

Developmental biology - 15 Sept 2008

Hyenne Vincent, Desrosiers Marianne, Labbé Jean-Claude

Abstract excerpt

The evolutionary conserved PAR proteins control polarization and asymmetric division in many organisms. Recent work in Caenorhabditis elegans demonstrated that nos-3 and fbf-1/2 can suppress par-2(it5ts) lethality, suggesting that they participate in cell polarity by regulating the function of the anterior PAR-3/PAR-6/PKC-3 proteins. In Drosophila embryos, Nanos and Pumilio are homologous to NOS-3 and FBF-1/2...

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PMID: 18652816
DOI: 10.1016/j.ydbio.2008.06.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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