Article
Polymorphism of a COLIA1 gene Sp1 binding site in Korean women with pelvic organ prolapse.
Yonsei medical journal - 31 Aug 2009
Cho Hye Jin, Jung Hyun Joo, Kim Sei Kwang, Choi Jong Rak, Cho Nam Hoon, Bai Sang Wook
Abstract excerpt
PURPOSE: To evaluate the possible influence of G-->T substitution at the Sp1-binding site of the COLIA1 gene on the risk of pelvic organ prolapse (POP). MATERIALS AND METHODS: The study group consisted of 15 women with advanced stage POP. Fifteen control subjects with uterine myomas among the postmenopausal women were matched for age and parity. DNA was obtained from peripheral blood leukocytes. The fragments of...
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