Article
Variation in STAT4 is associated with systemic lupus erythematosus in a Finnish family cohort.
Annals of the rheumatic diseases - 1 May 2010
Hellquist Anna, Sandling Johanna K, Zucchelli Marco, Koskenmies Sari, Julkunen Heikki, D'Amato Mauro, Garnier Sophie, Syvänen Ann-Christine, Kere Juha
Abstract excerpt
OBJECTIVES: To investigate whether 10 single nucleotide polymorphisms (SNPs) and haplotypes in the STAT4 gene, previously associated with systemic lupus erythematosus (SLE) in a Swedish case-control cohort, are also associated with SLE risk in a Finnish SLE family cohort. METHOD: Genotyping was performed in 192 Finnish families, with 237 affected subjects and their healthy relatives, using the SNPstream...
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