Glutathione S-transferase and P-glycoprotein in multidrug resistant Chinese hamster cells.

doi:10.1016/0006-2952(90)90106-u

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Article

Glutathione S-transferase and P-glycoprotein in multidrug resistant Chinese hamster cells.

Biochemical pharmacology - 1 Jun 1990

Medh R D, Gupta V, Zhang Y, Awasthi Y C, Belli J A

Abstract excerpt

Glutathione S-transferases (GSTs) have been reported to be elevated in some forms of hepatic carcinogenesis, in multidrug resistant (MDR) cells exhibiting elevated P-glycoprotein, and in cells resistant to alkylating agents independent of the MDR phenotype. The reported elevation of GST in associ...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Animals
Cell Line
Cricetinae
Cricetulus
Doxorubicin
Drug Resistance
Glutathione Transferase
Membrane Glycoproteins
Phenotype

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