Glutathione S-transferase and multidrug-resistant phenotype in transitional cell carcinoma of the bladder.

doi:10.1159/000473801

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Article

Glutathione S-transferase and multidrug-resistant phenotype in transitional cell carcinoma of the bladder.

European urology - 1 Jan 1996

Akdaş A, Türkeri L N, Küllü S, Tarcan T, Sakr W, Grignon D J

Abstract excerpt

OBJECTIVE: To asses the role of expression of resistance phenotypes in treatment failure in patients with invasive transitional cell carcinoma of the urinary bladder, since P-glycoprotein and glutathione S-transferase pi (GST) expression are implicated in resistance to various chemotherapy agents...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Carcinoma, Transitional Cell
Genes, MDR
Glutathione Transferase
Humans
Immunohistochemistry
Phenotype
Urinary Bladder
Urinary Bladder Neoplasms

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