Article
Glutathione S-transferase and multidrug-resistant phenotype in transitional cell carcinoma of the bladder.
European urology - 1 Jan 1996
Akdaş A, Türkeri L N, Küllü S, Tarcan T, Sakr W, Grignon D J
Abstract excerpt
OBJECTIVE: To asses the role of expression of resistance phenotypes in treatment failure in patients with invasive transitional cell carcinoma of the urinary bladder, since P-glycoprotein and glutathione S-transferase pi (GST) expression are implicated in resistance to various chemotherapy agents in different tumors. METHODS: Tumor samples from P-glycoprotein and GST-pi were analyzed by immunohistochemistry....
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