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Primordial germ cells contain subpopulations that have greater ability to develop into pluripotential stem cells.

Development, growth & differentiation - 1 Sept 2009

Matsui Yasuhisa, Tokitake Yuko

Abstract excerpt

Primordial germ cells (PGCs) are undifferentiated germ cells in embryos. We previously found that some mouse PGCs develop into pluripotential cells (EG cells) when cultured on a feeder layer expressing the membrane bound form of Steel factor with culture medium containing leukemia inhibitory factor and basic fibroblast growth factor. To understand the mechanisms of the conversion of PGCs into EG cells, we...

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Source

Identifiers

PMID: 19712268
DOI: 10.1111/j.1440-169X.2009.01125.x

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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