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Article

Polymorphisms of DNA base-excision repair genes APE/Ref-1 and XRCC1 are not associated with the risk for Graves' disease.

Cell biochemistry and function - 1 Oct 2009

Doğru-Abbasoğlu Semra, Tanrikulu Sevda, Ademoğlu Evin, Erbil Yeşim, Ozderya Ayşenur, Karadağ Berrin, Uysal Müjdat

Abstract excerpt

Oxidative stress has been implicated in etiopathogenesis of Graves' disease (GD). Increased lipid peroxidation and oxidative DNA damage have been found in GD patients. Oxidative DNA damage is mainly repaired by the base-excision repair (BER) pathway. Polymorphisms in DNA-repair genes have been associated with the increased risk of various diseases and could also be related to the etiology of GD. Therefore, we...

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Identifiers

PMID: 19711438
DOI: 10.1002/cbf.1595

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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