Article
The A946T polymorphism in the interferon induced helicase gene does not confer susceptibility to Graves' disease in Chinese population.
Endocrine - 1 Oct 2007
Zhao Ze-Fei, Cui Bin, Chen Hao-Yan, Wang Shu, Li Imelda, Gu Xue-Jiang, Qi Li, Li Xiao-Ying, Ning Guang, Zhao Yong-Ju
Abstract excerpt
Genetic susceptibility plays a major role in the etiology of Graves' disease (GD). A recent study revealed that the A946T polymorphism (rs1990760) in interferon induced helicase (IFIH1) gene was a susceptible locus for GD. A case-control study in a Chinese population was undertaken, with 261 GD patients and 206 healthy subjects, to analyze the association of A946T polymorphism in IFIH1 gene with GD. In addition,...
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