Article
Genetic polymorphisms in DNA repair gene APE1, XRCC1 and XPD and the risk of pre-eclampsia.
European journal of obstetrics, gynecology, and reproductive biology - 1 Oct 2009
Vural Pervin, Değirmencioğlu Sevgin, Doğru-Abbasoğlu Semra, Saral Neslihan Y, Akgül Cemil, Uysal Müjdat
Abstract excerpt
OBJECTIVE: Oxidative stress has been postulated as a major contributor to placental hypoperfusion and ischemia in pre-eclampsia (PE). Reactive oxygen species (ROS) generated during placental ischemia can cause oxidative damage to nucleic acids. Base excision repair (BER) and nucleotide excision r...
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