Article
Endothelial response to childhood infection: the role of mannose-binding lectin (MBL).
Atherosclerosis - 1 Jan 2010
Charakida Marietta, Donald Ann E, Leary Sam, Halcox Julian P, Turner Malcolm W, Johnson Marina, Loukogeorgakis Stavros P, Okorie Michael I, Davey Smith George, Deanfield John E, Klein Nigel J
Abstract excerpt
OBJECTIVE: To assess the influence of mannose-binding lectin (MBL) genotype on endothelial function in the presence and absence of infection in childhood. METHODS: We studied 2176 children aged 10 years drawn from the Avon Longitudinal Study of Parents and Children. Endothelial function was assessed by flow mediated dilatation (FMD). Exon 1 and promoter polymorphisms in the MBL gene were determined by...
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