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Harnessing Plant Biodiversity for the Discovery of Novel Anticancer Drugs Targeting Microtubules

4 May 2017

Abstract excerpt

The microtubule cytoskeleton plays a critical role in a wide range of cellular activities and has been shown to be a highly effective target for the treatment of human malignancies. Despite the recent focus on proteomics and high-throughput profiling, it is clear that analysis of plant extracts has yielded several highly efficacious microtubule-targeting agents (MTAs) currently in clinical use, as well as agents...

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PMID: 28523014
DOI: 10.3389/fpls.2017.00720

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