Article
Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen.
Cancer research - 1 Jul 2007
Rebacz Blanka, Larsen Thomas O, Clausen Mads H, Rønnest Mads H, Löffler Harald, Ho Anthony D, Krämer Alwin
Abstract excerpt
A major drawback of cancer chemotherapy is the lack of tumor-specific targets which would allow for the selective eradication of malignant cells without affecting healthy tissues. In contrast with normal cells, most tumor cells contain multiple centrosomes, associated with the formation of multip...
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