Article
Analysis and characterization of the interleukin 2 receptor alpha and beta chain expression in CD4-CD8- cells.
Scandinavian journal of immunology - 1 Apr 1990
Gutiérrez-Ramos J C, Pezzi L, Leonardo E, Martin C, Martínez C
Abstract excerpt
The differential effects that the binding of interleukin 2 (IL-2) to its beta or alpha beta receptors might induce in two different CD4-CD8- T-cell lines were analysed. While LD1.T3b, a double-negative T cell derived from MRL/lpr mice, constitutively expressed high levels of the IL-2R beta chain, YAC-1, a Moloney sarcoma virus-transformed CD4-CD8- T cell, expressed (as an activated T cell) the beta and alpha...
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